정재창 교수님 (Jung, Jea Chang)

정재창 교수님 주요이력

학력	석사 : 경북대 Kyungpook National University, Korea Comparison of some properties of mouse liver and kidney alkaline phosphatase.
	박사 : 경북대 Kyungpook National University, Korea A possible role of transforming growth factor-β2 (TGF- β2) in the chondrogenic differentiation of chick limb bud mesenchymal cells
주요 경력	Mar. 2002 - Present: Professor, Dept. of Biology, Kyungpook National Univ. Daegu, Korea
	Sep. 2010 - Aug. 2011: Visiting Professor in Schepens Eye Research Institute/Massachusetts Eye and Ear/Harvard, Boston, MA
	Oct. 2001 - Feb. 2002: Research Professor in Hospital of Kyungpook National University.
	Jan. 1998 - Sep. 2001: Research fellow in Department of Ophthalmology, New England Medical Center/Tufts University, Boston, MA
	Dec. 1996 - Dec. 1997: Research fellow in Department of Pathology, University of Pennsylvania, Philadelphia, PA
	Sep. 1995 - Nov. 1996: Research fellow in Department of Biology, University of Dayton, Dayton, OH

대표 논문 자료

2013년

• Kim HK, kang MK, Jung KH, Kang SH, Kim YH, Jung JC, Lee GH, Chang Y, Kim TJ (2013)
  Gadolinium Complex of DO3A-benzothiazole Aniline (BTA) Conjugate as a Theranostic Agent. J Med Chem. 56(20):8104-8111.
• Huh MI, Jung JC (2013)
  Expression of matrix metalloproteinase-13 (MMP-13) in the testes of growing and adult chicken. Acta Histochem. 115(5):475-480.
• Paudel S, Kim YH, Huh MI, Kim SJ, Chang Y, Park YJ, Lee KW, Jung JC (2013)
  ADAM10 mediates N-cadherin ectodomain shedding during retinal ganglion cell differentiation in primary cultured retinal cells from the developing chick retina. J Cell Biochem. 114(4):942-954.

2012년

• Kim YH, Jung JC (2012) Suppression of tunicamycin-induced CD44v6 ectodomain shedding and apoptosis is correlated with temporal expression patterns of active ADAM10, MMP-9 and MMP-13 proteins in Caki-2 renal carcinoma cells. Oncol Rep. 28(5):1869-1874.
• Lee SK, Shehzad A, Jung JC, Sonn JK, Lee JT, Park JW, Lee YS (2012) Protein kinase Cα protects against multidrug resistance in human colon cancer cells. Mol Cells. 34(1):61-69.
• Kim YH, Chang Y, Jung JC (2012) Staurosporine induces ganglion cell differentiation in part by stimulating urokinase-type plasminogen activator expression and activation in the developing chick retina. Biochem Biophys Res Commun. 423(1):67-72.

2011년

• Bae JE, Huh MI, Ryu BK, Do JY, Jin SU, Moon MJ, Jung JC, Chang Y, Kim E, Chi SG, Lee GH, Chae KS (2011) The effect of static magnetic fields on the aggregation and cytotoxicity of magnetic nanoparticles. Biomaterials. 32(35):9401-9414.

2010년

• Jin EJ, Park KS, Kim D, Lee YS, Son JK, Jung JC, Bang OS, Kang SS (2010) TGF-β3 inhibits chondrogenesis by suppressing precartilage condensation through stimulation of N-cadherin shedding and reduction of cRREB-1 expression. Mol Cells. 29(4):425-32.
• Park JA, Kim HK, Kim JH, Jeong SW, Jung JC, Lee GH, Lee J, Chang Y, Kim TJ (2010) Gold nanoparticles functionalized by gadolinium-DTPA conjugate of cysteine as a multimodal bioimaging agent. Bioorg Med Chem Lett. 1;20(7):2287-91.

2009년

• Park JY, Baek MJ, Choi ES, Woo S, Kim JH, Kim TJ, Jung JC, Chae KS, Chang Y, Lee GH (2009) Paramagnetic Ultrasmall Gadolinium Oxide Nanoparticles as Advanced T-1 MR1 Contrast Agent: Account for Large Longitudinal Relaxivity, Optimal Particle Diameter, and In Vivo T-1 MR Images. ACS Nano. 24;3(11):3663-9.
• Huh MI, Chang Y, Jung JC (2009) Temporal and spatial distribution of TGF-β isoforms and signaling intermediates in corneal regenerative wound repair (2009) Histol Histopathol. 24(11):1405-16.
• Huh MI, Kim YH, Park JH, Bae SW, Kim MH, Chang Y, Kim SJ, Lee SR, Lee YS, Jin EJ, Sonn JK, Kang SS, Jung JC (2009) Distribution of TGF-β Isoforms and Signaling Intermediates in Corneal Fibrotic Wound Repair. J Cell Biochem. 1;108(2):476-88.
• Jung JC, Wang PX, Zhang G, Ezura Y, Fini ME, Birk DE (2009) Collagen fibril growth during chicken tendon development: matrix metalloproteinase-2 and its activation Cell Tissue Res. 336(1):79-89.

2008년

• Park JA, Lee JJ, Jung JC, Yu DY, Oh C, Ha S, Kim TJ, Chang Y (2008) Gd-DOTA Conjugate of RGD as a Potential Tumor-Targeting MRI Contrast Agent. Chembiochem. 24;9(17):2811-3.
• Dutta S, Park JA, Jung JC, Chang Y, Kim TJ (2008) Gd-complexes of DTPA-bis(amide) conjugates of tranexamic acid and its esters with high relaxivity and stability for magnetic resonance imaging. Dalton Trans. 28;(16):2199-206.
• Park BH, Jung JC, Lee GH, Kim JT, Lee YJ, Kim JY, Kim YW, Jeong JH, Chang Y (2008) Comparison of labeling efficiency of different magnetic nanoparticles into stem cell. Colloids and Surfaces A: Physicochem. Eng. Aspects 313–314:145–149.
• Park BH, Chang Y, Lee YJ, Park JA, Kim IS, Bae SJ, Lee GH, Kim TJ, Kim JY, Kim HJ, Jung JC (2008) Targeting of membrane type 1-matrix metalloproteinase (MT1-MMP) using superparamagnetic nanoparticles in human liver cancer cells. Colloids and Surfaces A: Physicochem. Eng. Aspects 313–314:647–650.
• Jin EJ, Lee SY, Jung JC, Bang OS, Kang SS (2008) TGF-β3 inhibits chondrogenesis of cultured chick leg bud mesenchymal cells via downregulation of connexin 43 and integrin beta 4. J Cell Physiol. 214(2):345-53.

2007년

• Lee JW, Park JA, Lee JJ, Bae SJ, Lee SH, Jung JC, Kim MN, Lee J, Woo S, Chang Y (2007) Manganese-enhanced auditory tract-tracing MRI with cochlear injection. Magn Reson Imaging. 25(5):652-6.
• Jung JC, Huh MI, Fini ME (2007) Constitutive collagenase-1 synthesis through MAPK pathways is mediated, in part, by endogenous IL-1 alpha during fibrotic repair in corneal stroma. J Cell Biochem. 1;102(2):453-62.
• Lee JH, Yu SM, Yoon EK, Lee WK, Jung JC, Kim SJ (2007) 15-deoxy-Delta(12,14)-prostaglandinJ2 regulates dedifferentiation through peroxisome proliferator-activated receptor-gamma-dependent pathway but not COX-2 expression in articular chondrocytes J Korean Med Sci. 22(5):891-7.
• Lee YA, Kang SS, Baek SH, Jung JC, Jin EJ, Tak EN, Sonn JK (2007) Redifferentiation of dedifferentiated chondrocytes on chitosan membranes and involvement of PKC alpha and p38 MAP kinase. Mol Cells. 24(1):9-15.
• Huh MI, Lee YM, Seo SK, Kang BS, Chang Y, Lee YS, Fini ME, Kang SS, Jung JC (2007) Roles of MMP/TIMP in regulating matrix swelling and cell migration during chick corneal development. J Cell Biochem. 101(5):1222-37.
• Lee JW, Park JA, Lee JJ, Bae SJ, Lee SH, Jung JC, Kim MN, Lee J, Woo S, Chang Y (2007) Manganese-enhanced auditory tract-tracing MRI with cochlear injection Magn Reson Imaging. 25(5):652-6.

2006년

• Jin EJ, Lee SY, Choi YA, Jung JC, Bang OS, Kang SS (2006) BMP-2-enhanced chondrogenesis involves p38 MAPK-mediated down-regulation of Wnt-7a pathway. Mol Cells. 31;22(3):353-9.

2004년

• Park EK, Kim MS, Lee SH, Kim KH, Park JY, Kim TH, Lee IS, Woo JT, Jung JC, Shin HI, Choi JY, and Kim SY (2004) Furosin, an ellagitannin, suppresses RANKL-induced osteoclast differentiation and function through inhibition of MAP kinase activation and actin ring formation. Biochem Biophys Res Commun. 24;325(4):1472-80.
• Jung JC, West-Mays JA, Stramer BM, Byrne MH, Scott S, Mody MK, Sadow PM, Krane SM, Fini ME (2004) Activity and expression of Xenopus laevis matrix metalloproteinases: Identification of a novel role for the hormone prolactin in regulating collagenolysis in both amphibians and mammals. J Cell Physiol. 201(1):155-64.
• Kim KH, Park GT, Lim YB, Rue SW, Jung JC, Sonn JK, Bae YS, Park JW, Lee YS (2004) Expression of connective tissue growth factor, a biomarker in senescence of human diploid fibroblasts, is up-regulated by a transforming growth factor-β-mediated signaling pathway. Biochem Biophys Res Commun. 11;318(4):819-25.
• Jung JC, Park GT, Kim KH, Woo JH, An JM, Kim KC, Chung HY, Bae YS, Park JW, Kang SS, Lee YS (2004) Differential expression of transforming growth factor-β in the interstitial tissue of testis during aging. J Cell Biochem. 1;92(1):92-8.
• Stramer BM, Kwok MG, Farthing-Nayak PJ, Jung JC, Fini ME, Nayak RC (2004) Monoclonal antibody (3G5)-defined ganglioside: Cell surface marker of corneal keratocytes. Invest Ophthalmol Vis Sci. 45(3):807-12.

2003년

• Stramer BM, Zieske JD, Jung JC, Austin JS, Fini ME (2003) Molecular mechanisms controlling the fibrotic repair phenotype in cornea: Implications for surgical outcomes. Invest Ophthalmol Vis Sci. 44(10):4237-46.
• Kim SW, Oh HM, Kim BS, Chung HT, Han WC, Kim EC, Kim TH, Seo GS, Lyou JH, Nah YH, Jung JC, Choi SC, Jun CD (2003) Soluble factor from tumor cells induces heme oxygenase-1 by a nitric oxide-independent mechanism in murine peritoneal macrophages. Exp Mol Med. 28;35(1):53-9.

2002년

• Wang X, Mori T, Jung JC, Fini ME, Lo EH (2002) Secretion of matrix metalloproteinase-2 and-9 after mechanical trauma injury in rat cortical cultures and involvement of MAP kinase. J Neurotrauma. 19(5):615-25.
• Mori T, Wang X, Jung JC, Sumii T, Singhal AB, Fini ME, Dixon CE, Alessandrini A, Lo EH (2002) Mitogen activated protein kinase inhibition for traumatic brain injury: In vitro and in vivo effects. J Cereb Blood Flow Metab. 22(4):444-52.
• Jung JC, Leco KJ, Edwards DR, Fini ME (2002) Matrix metalloproteinases mediate the dismantlingof mesenchymal structures in the tadpole tail during thyroid hormone-indeced tail resorption. Dev Dyn. 223(3):402-13.
• Lee JK, Jung JC, Chun JS, Kang SS, Bang OS (2002) Expression of p21WAF1 is dependent on the activation of ERK duting vitamin E- succinate-induced monocytic differentiation. Mol Cells. 28;13(1):125-9.
• Hargrave SL, Jung JC, Fini ME, Gelender H, Cather C, Guidera A, Udell I, Fisher S, Jester JV, Bowman RW, McCulley JP, Cavanagh HD (2002) The effect of topical diclofenac on Matrix metalloproteinase expression: An analysis of postoperative keratolysis. Ophthalmology. 109(2):343-50.
• Jung, J.C, Mohan R, Chintala SK, Villar WV, McCabe F, Russo LA, Lee Y, McCarthy BE, Wollenberg KR, Jester JV, Wang M, Welgus HG, Shipley JM, Senior RM, Fini ME (2002) Matrix Metalloproteinase Gelatinase B (MMP-9) coordinates and effects epithelial regeneration. J Biol Chem. 18;277(3):2065-72.

2001년

• Asahi M, Wang X, Mori T, Sumii T, Jung JC, Moskowitz MA, Fini ME, Lo EH (2001) Effects of Matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia. J Neurosci. 1;21(19):7724-32.

2000년

• Asahi M, Asahi K, Jung JC, del Zoppo GJ, Fini ME, Lo EH (2000) Role for matrix metalloproteinase 9 after focal cerebral ischemia: effects of gene knockout and enzyme inhibition with BB-94. J Cereb Blood Flow Metab. 20(12):1681-9.
• Wang X, Jung J, Asahi M, Chwang W, Russo L, Moskowitz MA, Dixon CE, Fini ME, Lo EH. (2000) Effects of matrix metalloproteinase-9 gene knockout on morphological and motor outcomes after traumatic brain injury. J Neurosci. 15;20(18):7037-42.

1998년

• Jung JC, Tsonis PA (1998) Role of 5' HoxD genes in chondrogenesis in vitro. Int J Dev Biol. 42(4):609-15.
• Jung JC, Del Rio-Tsonis K, Tsonis PA (1998) Regulation of Homeobox-containing genes during lens regeneration. Exp Eye Res. 66(3):361-70.

1997년

• Jung JC, Del Rio-Tsonis K, Chiu IM, Tsonis PA Chiu, Ing-Ming., and Tsonis, P.A (1997) Conservation of fibroblast growth factor function in lens regeneration. Proc Natl Acad Sci U S A. 9;94(25):13701-6.

1996년

• Tsonis PA, Sargent MT, Del Rio-Tsonis K, Jung JC (1996) 9-cis retinoic acid antagonizes the Stimulatory effect of 1,25-dihydroxyvitamin D3 on chondrogenesis of chick limb bud mesenchymal cells: interactions of their receptors. Int J Dev Biol. 40(5):1053-9.

1995년

• Park SY, Jung JC, Kim SD, Lee YS, Park TK, Kang SS (1995) cAMP induces phosphorylation of a 40-kDa nuclear protein which is distinct from CREB during chondrogenesis of chick limb bud mesenchymal cells in vitro. Biochem Biophys Res Commun. 6;212(1):16-20.
• Jung JC, Kang SS (1995) The promoting effect of Transforming growth factor-β2 in the chondrogenic differentiation. Kor. J. Zool. 38:20-25.

1994년

• Shin YS, Seo SR, Jung JC, Lee Y., Park TK, Kang SS (1994) Promoting effects of forskolin on chondrogenic differentiation in vitro. Mol Cells. 4: 515-518.

1992년

• Sonn JK, Jung JC, Park TK (1992) Role of protein kinase C during the chondrogenesis in vitro. J Grad Sch Edu KNU. 24: 91-101.

1991년

• Kang SS, Jun CD, Jung JC, Chung HT, Park TK (1991) A possible role of protein kinase C in the chondrogenesis of chick limb bud mesenchyme cells. Mol Cells. 1: 475-481.

1986년

• Jung JC, Kang SS (1986) Comparison of some properties of mouse liver and kidney alkaline phosphatase. Res Rev Kyungpook Nat'l. Univ. 41: 335-344.